Aiyuk signed a lucrative new deal with the 49ers last offseason. He played in seven games, catching 25 passes for 374 yards.

While Jerry Rice has guarded optimism the 49ers can rally around a young defense, he insists that Brandon Aiyuk should not be ...

Brandon Aiyuk is expected to start the season on reserve/physically unable to perform as he continues his recovery from knee ...

Aiyuk would have to miss at least four games if he starts the regular season on the PUP list. The star wideout tore his ACL ...

San Francisco 49ers wide receiver Brandon Aiyuk reportedly could start the regular season on the reserve/physically unable to ...

The 49ers and their fans continued to wonder about the health of Brandon Aiyuk. He received an important update Thursday.

According to NBC Sports Bay Area’s Matt Maiocco, Aiyuk has an outside chance of returning before that. Here’s what Maiocco ...

An ACL tear limited Brandon Aiyuk to seven games last season. Given the timing of the injury, it has long been a question ...

The San Francisco 49ers are waiting on Brock Purdy's weapon Brandon Aiyuk to come back from injury. Kyle Shanahan's playbook is too deep to waste.

The San Francisco 49ers may not have to wait too deep into the regular season for one of their stars to return to from injury.

The Steelers, who traded for former Seattle Seahawks star DK Metcalf and sent George Pickens to the Dallas Cowboys in two bold offseason deals, were rumored to be interested in Aiyuk again, and Pro ...

Brandon Aiyuk is expected to start the season on reserve/physically unable to perform as he continues his recovery from ...