San Francisco 49ers coach Kyle Shanahan spoke to reporters on Wednesday at an end-of-the-season press conference in Santa Clara.

49ers general manager John Lynch confirmed wide receiver Brandon Aiyuk has played his last snap in San Francisco as the team ...

A recent theory has emerged linking the proximity of the 49ers' practice facility to an electrical substation.

Kyle Shanahan explains Ricky Pearsall's injury setbacks and why San Francisco remains optimistic about the young receiver's ...

The San Francisco 49ers ended their season against the Seattle Seahawks in an abrupt manner. The devastating 41-6 loss for ...

John Lynch and the 49ers are willing to look into anything that might be contributing to San Francisco's rash of injuries.

The 49ers shared key injury updates on Nick Bosa, George Kittle, Alfred Collins, and several others during their annual ...

San Francisco 49ers are one of the most injured teams in the NFL. Conspiracy theorists have developed a theory as to why that ...

John Lynch said the 49ers are looking into the viral conspiracy about the electrical substation next to San Francisco’s ...

Losing brutally to the Seahawks in the playoffs has the 49ers shamelessly hanging onto excuses.

Latest updates after Christian McCaffrey suffered a stinger injury in the 49ers game vs Seahawks in Saturday's playoff game.

The Seattle Seahawks are dealing with a troubling injury heading into Saturday's NFC Divisional Round game against the San ...