Hydroxyzine (whose brand names include Vistaril) and Benadryl (the brand name of diphenhydramine) are both first-generation antihistamines and share many similarities, including sedating side effects.

The first antihistamine that the Food and Drug Administration approved was diphenhydramine. The compound was created in 1943, and the Parke-Davis pharmaceutical company brought it to market in 1946 ...

Back away from the medicine cabinet. The US Consumer Product Safety Commission (CPSC) just announced a recall of more than 2,300 bottles of a popular allergy medication due to a serious child ...

(CNN) - Some doctors say people with allergies may want to take something other than the drug diphenhydramine, which is sold under the brand name Benadryl. Allergy experts from Johns Hopkins ...

The challenge, made popular on social media site TikTok, involves ingesting large amounts of over-the-counter medicine.

Two girls were able to avoid grave circumstances after telling Lafayette police they intentionally took a large amount of ...

Doctors are taking aim at a medicine cabinet staple, arguing its risks outweigh its benefits. Millions of adults and children take over-the-counter (OTC) diphenhydramine, the active ingredient in ...