Healio

Rheumatologists view CAR T-cell therapy as ‘revolutionary,’ but cost, safety temper enthusiasm

Although rheumatologists consider chimeric antigen receptor T-cell therapy “potentially transformative,” nearly 70% remain ...
Hosted on MSN

Enhanced CAR T cells emerge from genetic screening

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...
The Scientist

CAR T Cells Break Tumor Defenses with Trojan Horse Strategy

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

Experimental CAR T therapy targets tumor's immune shield, not cancer cells directly

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells ...
Medscape

Novel CAR T Cells Show Promise for Resistant T-Cell ALL

In a phase 1 study, anti-CD7 chimeric antigen receptor (CAR) T cells induced complete remission in children and adults with relapsed or refractory T-cell acute lymphoblastic leukemia (ALL), with 82% ...
Fred Hutch

For many blood cancer patients, CAR T-cell therapy is game-changing

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...
GEN

Next-Gen CAR T Cells Destroy Cancer Cells with Fewer Toxic Effects in Mice

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...