Recent therapies like hydroxyurea (Droxia, Bristol-Myers Squibb), the first FDA-approved drug for SCD in 1994, increase fetal hemoglobin (HbF), which, through unknown pathways, improves SCD symptoms ...

Sickle cell anemia (HbSS) is the homozygous dominant variant and the most common and severe form of the disease. Whereas patients who only inherited one gene encoding for abnormal HbS and a different ...

Today, Kwincy Lassiter is a 25-year-old student enjoying a second chance at life. However, the first 16 years of his sickle cell journey looked much different.

A new breakthrough study led by researchers at the University of Minnesota Twin Cities could explain why patients with the same genetic sickle cell mutation experience different levels of pain, organ ...

Cristina Pina receives funding from Children's Cancer and Leukaemia Group via the Little Princess Trust and the National Centre for the Replacement, Reduction and Refinement of Animals in Research.