New research advances our understanding of the gating mechanism of the CFTR, the chloride channel mutated in cystic fibrosis patients. The study by Tzyh-Chang Hwang and colleagues (University of ...

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to ...

A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists ...

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart ...

Expert Rev Proteomics. 2009;6(4):421-431. Thus far, many groups have been working in the study of serum protein changes during the development of liver fibrosis. [54–58] It was of great clinical ...

The proof-of-concept study also identified key metabolites that correlated with pulmonary fibrosis diagnosis and disease progression. Fibrotic interstitial lung disease is often diagnosed late because ...

Finding a biological mechanism much like an online social network, scientists have identified the bacterial protein VpsT as the master regulator in Vibrio, the cause of cholera and other enteric ...