The pathogenesis of idiosyncratic “hypersensitivity” reactions to the sulphonamides is thought to be mediated by reactive intermediates. We have previously demonstrated dose-related toxicity of ...
ON addition of a small amount of phenyl hydroxylamine (C 6 H 5.NHOH) to a fresh alkaline solution of hæmatin prepared from hæmin crystals, the colour of the solution turns rapidly from brown to bright ...