The overall goal of this project is to identify new therapies that target influenza virus replication. The global health burden of annual influenza epidemics coupled with the emergence of highly ...

Structure of the influenza virus replication complex, comprising two viral polymerases (dark and light colours) in interaction with human ANP32 (purple). In recent years, public health measures, ...

Researchers uncover how a key human immune protein curbs H5N1 avian flu, but the virus is evolving—could we be on the brink of a new zoonotic threat? Research Letter: Replication Restriction of ...

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...