Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths ...

(Nanowerk Spotlight) Scientists have long sought to decode the complex communication between cellular organelles that regulates virtually all aspects of human health and disease. Mitochondria and ...

The interactions within and between the organelles inside our cells could hold the key to understanding complex diseases such as cancer and neurodegeneration. Recent advances in imaging techniques are ...

Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular signaling pathways, but the mechanisms that control the endocytosis itself are largely ...

Mitochondria generate most of the cell’s energy. However, when they become dysfunctional, damaged, or old, mitochondria can turn into pro-death organelles, which produce reactive oxygen species that ...

Traditional electron microscopy techniques include scanning electron microscopy (SEM) and transmission electron microscopy (TEM), where electrons that interact with the sample are imaged. 4 The ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...