For the second season in a row, the San Francisco 49ers are being hit hard by key injuries. Wide receiver Brandon Aiyuk is still out after tearing his ACL and MCL last October, and this past Sunday, ...

Two years on, Jones lived up to what Orlovsky said in their win against the Saints, and Colin Cowherd has concluded that ...

Jalen Ramsey is considered one of the best NFL trash talkers as a defensive cornerback. The playing style of Ramsey sees him having speed and catlike reflexes once defending wide receivers to ...

NEW ORLEANS – Brock Purdy carefully put on his sock and sneaker over a slightly swollen but not discolored big toe, the right ...

Mac Jones started for San Francisco and looked comfortable as Christian McCaffrey helped carry the offense, too ...

San Francisco 49ers fullback Kyle Juszczyk has been ruled out for the rest of the team's battle with the New Orleans Saints ...

Even with Brock Purdy out, Christian McCaffrey and San Francisco have what it takes to pick up a road win in New Orleans on ...

Heading into this matchup, there's a real chance Moore can land his first win as the head coach of the Saints. The 49ers roll ...

USA Today's NFL experts make their picks for a Week 2 showdown between the New Orleans Saints and San Francisco 49ers ...

Las Vegas tight end Brock Bowers is expected to play in the Monday night doubleheader after injuring his knee last week. He’s too good to sit, though it would help his backers to have a last-second ...

Dallas signed Smith, its starting left guard, to a four-year, $96 million extension, per NFL Media. The deal includes $81.2 million guaranteed, with the $24 million average annual salary an NFL record ...

The 49ers enter Sunday’s game in New Orleans seeking to open a season with back-to-back road wins like in 2019, ’21 and ’23.