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0:59
YouTube
MedLecturesMadeEasy
Mechanism of action of opioids
Opioid agonists produce analgesia by binding to G protein-coupled receptors (GPCRs) in the brain and spinal cord regions involved in the transmission and modulation of pain Opioid drugs mimic endogenous compounds: endorphins, enkephalins, and dynorphins that bind to opioid receptors. Four opioid receptor types: mu (μ), kappa (κ), delta (δ ...
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DopeSick USA on Instagram: "THE BIG HOMIE @mohawkmatt_sfv just dropped his latest design collab with DopeSick Apparel: FREEDOM FIRST – “THE TRUTH SHALL SET YOU FREE” — a bold black crewneck sweatshirt with a POWERFUL VERSE. Rooted in STEP 1 of the 12 STEPS, Matt believes that when an addict gets honest with oneself and tells the truth, REAL FREEDOM begins. ✅ Limited drop. Crewneck available now—link in bio."
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